Wen-Chien Ko Selected Research

Therapeutics

1/2024	Haemolysin Ahh1 secreted from Aeromonas dhakensis activates the NLRP3 inflammasome in macrophages and mediates severe soft tissue infection.
9/2023	Clinical impact of the combination of rapid species identification and antifungal stewardship intervention in adults with candidemia.
8/2023	COVID-19-associated candidiasis and the emerging concern of Candida auris infections.
7/2023	Geographic patterns of antimicrobial susceptibilities for Bacteroides spp. worldwide: Results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) programme, 2007-2020.
2/2023	Integration of antimicrobial stewardship intervention with rapid organism identification improve outcomes in adult patients with bloodstream infections.
12/2022	Reappraisal of the clinical role of metronidazole therapy for Clostridioides difficile infection in Taiwan: A multicenter prospective study.
12/2022	The first case of Francisella novicida infection in Taiwan: bacteraemic pneumonia in a haemodialysis adult.
2/2022	Oral Nirmatrelvir/Ritonavir Therapy for COVID-19: The Dawn in the Dark?
1/2022	Effect of Doxycycline in Decreasing the Severity of Clostridioides difficile Infection in Mice.
1/2022	Effects of Inappropriate Administration of Empirical Antibiotics on Mortality in Adults With Bacteraemia: Systematic Review and Meta-Analysis.

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Wen-Chien Ko Research Topics

Disease

98	Infections 02/2024 - 11/2002
62	Bacteremia 12/2022 - 01/2004
29	Sepsis (Septicemia) 01/2024 - 07/2004
23	Pneumonia (Pneumonitis) 02/2024 - 07/2004
21	COVID-19 02/2024 - 01/2020
21	Critical Illness (Critically Ill) 08/2023 - 11/2007
12	Diarrhea 04/2023 - 04/2010
11	Urinary Tract Infections (Urinary Tract Infection) 06/2023 - 04/2011
11	Dengue (Dengue Fever) 04/2022 - 10/2016
10	Diabetes Mellitus 01/2023 - 10/2006
10	Cross Infection (Nosocomial Infection) 12/2022 - 01/2004
9	Clostridium Infections 12/2022 - 12/2014
9	Intraabdominal Infections 06/2022 - 08/2009
9	Neoplasms (Cancer) 12/2021 - 02/2013
9	Syphilis 04/2021 - 10/2010
8	Meningitis 01/2024 - 12/2004
8	Fever (Fevers) 02/2017 - 04/2004
6	Respiratory Tract Infections (Respiratory Tract Infection) 06/2022 - 09/2009
6	Thrombocytopenia (Thrombopenia) 01/2021 - 06/2012
6	Septic Shock (Toxic Shock Syndrome) 08/2020 - 10/2006
5	Soft Tissue Infections 01/2024 - 08/2011
5	Communicable Diseases (Infectious Diseases) 09/2023 - 05/2009
5	Community-Acquired Infections 01/2022 - 03/2003
5	Inflammation (Inflammations) 01/2022 - 11/2005
5	HIV Infections (HIV Infection) 12/2021 - 02/2009
5	Acquired Immunodeficiency Syndrome (AIDS) 02/2020 - 06/2007
5	Abscess 01/2020 - 06/2004
5	Liver Cirrhosis (Hepatic Cirrhosis) 08/2018 - 10/2006
5	Sexually Transmitted Diseases (Sexually Transmitted Disease) 01/2014 - 12/2009
4	Disease Progression 06/2020 - 04/2012
4	Peritonitis 02/2018 - 11/2005
3	Candidemia 09/2023 - 04/2006
3	Coinfection 12/2022 - 04/2021
3	Body Weight (Weight, Body) 01/2022 - 09/2009
3	Aspergillosis 01/2022 - 03/2016
3	Dyspnea (Shortness of Breath) 01/2022 - 02/2019
3	Severe Dengue 01/2022 - 05/2013
3	Hypertension (High Blood Pressure) 12/2021 - 08/2014
3	Hemorrhage 12/2021 - 02/2017

Drug/Important Bio-Agent (IBA)

46	Anti-Bacterial Agents (Antibiotics)IBA 02/2024 - 11/2003
31	Carbapenems (Carbapenem Antibiotics)IBA 06/2023 - 07/2004
14	Tigecycline (Tygacil)FDA Link 02/2024 - 11/2007
14	Vancomycin FDA LinkGeneric 12/2022 - 09/2009
14	beta-Lactamases (beta-Lactamase)IBA 06/2022 - 01/2004
12	VaccinesIBA 02/2024 - 05/2009
12	Anti-Infective Agents (Microbicides)IBA 08/2023 - 10/2006
11	FluoroquinolonesIBA 04/2021 - 11/2002
9	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2023 - 09/2002
9	Ciprofloxacin (Cipro)FDA LinkGeneric 12/2022 - 07/2003
9	Cefotaxime (Kendrick)FDA LinkGeneric 12/2022 - 11/2002
9	Ertapenem (Invanz)FDA Link 06/2022 - 11/2010
7	Metronidazole (Metric)FDA LinkGeneric 07/2023 - 01/2013
7	Cefepime (Maxipime)FDA LinkGeneric 10/2022 - 02/2013
7	Immunoglobulin M (IgM)IBA 04/2022 - 10/2016
7	Third Generation CephalosporinsIBA 01/2021 - 10/2006
6	Colistin (Coly-Mycin)FDA Link 02/2024 - 11/2007
6	carbapenemaseIBA 02/2024 - 01/2018
6	Proteins (Proteins, Gene)FDA Link 09/2023 - 12/2018
6	Imipenem FDA Link 06/2023 - 05/2011
6	Proton Pump InhibitorsIBA 01/2023 - 04/2015
6	AntigensIBA 04/2022 - 06/2010
6	Levofloxacin (Levaquin)FDA Link 04/2022 - 07/2003
6	Penicillins (Penicillin)FDA Link 04/2022 - 10/2010
5	Meropenem (Merrem)FDA LinkGeneric 02/2024 - 05/2011
5	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 07/2023 - 11/2014
5	Doxycycline (Periostat)FDA LinkGeneric 04/2023 - 08/2003
5	Cephalosporins (Cephalosporin Antibiotics)IBA 12/2022 - 07/2004
5	Moxifloxacin (Avelox)FDA Link 04/2022 - 07/2003
5	Immunoglobulin G (IgG)IBA 12/2020 - 10/2016
5	Cefazolin (Ancef)FDA LinkGeneric 01/2020 - 01/2010
5	C-Reactive ProteinIBA 01/2020 - 05/2012
4	Minocycline (Cyclops)FDA LinkGeneric 02/2024 - 11/2002
4	AntibodiesIBA 02/2024 - 06/2015
4	AzolesIBA 08/2023 - 09/2015
4	Fluconazole (Zonal)FDA LinkGeneric 08/2023 - 12/2004
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023 - 10/2012
4	16S Ribosomal RNAIBA 12/2022 - 06/2008
4	CytokinesIBA 01/2020 - 01/2012
4	ReaginsIBA 01/2020 - 10/2010
4	Transaminases (Aminotransferases)IBA 12/2019 - 04/2004
4	SteroidsIBA 09/2015 - 09/2010
4	Tetracycline (Achromycin)FDA LinkGeneric 02/2008 - 06/2002
3	RNA (Ribonucleic Acid)IBA 06/2023 - 02/2005
3	Ceftazidime (Fortum)FDA LinkGeneric 01/2023 - 01/2004
3	eravacyclineIBA 10/2022 - 01/2021
3	omadacyclineIBA 10/2022 - 01/2021
3	Linezolid (Zyvox)FDA Link 04/2022 - 05/2011
3	Ceftaroline FDA Link 08/2021 - 07/2020
3	COVID-19 VaccinesIBA 01/2021 - 01/2021
3	Methicillin (Metin)FDA Link 07/2020 - 11/2011
3	Sulbactam FDA LinkGeneric 01/2019 - 11/2007

Therapy/Procedure

95	Therapeutics 01/2024 - 11/2002
13	Length of Stay 09/2023 - 03/2006
6	Highly Active Antiretroviral Therapy (HAART) 04/2021 - 02/2009
6	Drug Therapy (Chemotherapy) 01/2020 - 12/2004
5	Long-Term Care 04/2021 - 09/2013
4	Catheters 08/2017 - 12/2011
3	Hand Hygiene 12/2022 - 04/2019
3	Patient Care Bundles 08/2019 - 08/2017
3	Home Nursing (Nursing, Home) 04/2019 - 11/2010